Which of the following transgenic human protein products has been used to treat emphysema?

Transgenic animals are developed by

Match the following:

Column-$I$	Column-$II$
$(1)$ Study of disease	$(p)$ Transgenic mice
$(2)$ Biological products	$(q)$ Testing toxicity of drug
$(3)$ Vaccine safety	$(r)$ Rheumatoid arthritis
$(4)$ Chemical safety	$(s)$ $\alpha-1$ Antitrypsin

Consider the following statements:
$I$. Transgenic animals are more sensitive to toxic substances than non-transgenic animals.
$II$. Useful biological products can be produced by introducing into transgenic animals the portion of $DNA$ which codes for a particular product.
$III$. Brazzein is a protein produced by a West African plant,$Pentadiplandra$ $brazzeana$,which is approximately $2000$ times as sweet as sugar.
Which of the statements given above are correct?

Transgenic animals are used for chemical safety testing. Identify the incorrect statement from the following.

What are animals called whose $DNA$ has been manipulated to possess and express an extra (foreign) gene?