At high temperatures,enzymes become .........

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(A) Enzymes are proteins that function optimally within a specific temperature range. When the temperature increases significantly beyond this optimal

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denatured

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(A) Enzymes are proteins that function optimally within a specific temperature range. When the temperature increases significantly beyond this optimal range,the weak bonds (such as hydrogen bonds) that maintain the enzyme's three-dimensional structure break. This process is known as denaturation. As a result,the active site of the enzyme loses its specific shape,rendering the enzyme unable to bind to its substrate and thus losing its catalytic activity.

Column $X$	Column $Y$
$(1)$ Aldolase	$(P)$ Hydrolases
$(2)$ Hexokinase	$(Q)$ Ligases
$(3)$ Succinic dehydrogenase	$(R)$ Lyases
$(4)$ Fructose isomerase	$(S)$ Oxidoreductases
$(5)$ Lactase	$(T)$ Transferases
$(6)$ Acetyl $CoA$ synthetase	$(U)$ Isomerases

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In homeotherms,the enzymatic reaction occurs best at . . . . . . °$C$.

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Which enzymes are responsible for changing the arrangement of atoms in substrate molecules?

Select the correct match for $X$ and $Y$:
Column $X$ Column $Y$
$(1)$ Aldolase $(P)$ Hydrolases
$(2)$ Hexokinase $(Q)$ Ligases
$(3)$ Succinic dehydrogenase $(R)$ Lyases
$(4)$ Fructose isomerase $(S)$ Oxidoreductases
$(5)$ Lactase $(T)$ Transferases
$(6)$ Acetyl $CoA$ synthetase $(U)$ Isomerases

Most of the enzymes work at an optimum temperature between . . . . . . .

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