Which of the following are considered second- | vedclass

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(C) Vaccines are categorized based on their production technology. $1.$ First-generation vaccines are whole-organism vaccines (live attenuated or inac

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Hepatitis $B$ vaccine

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(C) Vaccines are categorized based on their production technology. $1.$ First-generation vaccines are whole-organism vaccines (live attenuated or inactivated),such as the Smallpox vaccine,$D.P.T.$ (Diphtheria,Pertussis,Tetanus),and the Polio vaccine. $2.$ Second-generation vaccines are recombinant vaccines produced using genetic engineering techniques. $3.$ The Hepatitis $B$ vaccine is a classic example of a second-generation vaccine,as it is produced by expressing the Hepatitis $B$ surface antigen $(HBsAg)$ in yeast cells using recombinant $DNA$ technology. Therefore,the correct option is $C$.

Which of the following are considered second-generation vaccines?

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