Which of the following is correct regarding amino acids produced by microbes?

Curing of tea leaves is brought about by the activity of

The antibiotic penicillin was used to treat wounded $.....i....$ during $.....ii....$.

Match the following columns.

Column $I$	Column $II$
$1$. $Streptococcus$ $pneumoniae$	$(A)$ acetic acid
$2$. $Aspergillus$ $niger$	$(B)$ butyric acid
$3$. $Clostridium$ $butyricum$	$(C)$ streptokinase
$4$. $Acetobacter$ $aceti$	$(D)$ citric acid

Assertion $A$: $Ernest \text{ Chain}$ and $Howard \text{ Florey}$ improved the production of penicillin.
Reason $R$: Penicillin was obtained from the fungus $Penicillium \text{ notatum}$.
Which option is correct for Assertion $A$ and Reason $R$?

Yeast is used in the production of .......