Discuss briefly how a probe is used in molecular diagnostics.

Vedclass pdf generator app on play store
Vedclass iOS app on app store
(N/A) single-stranded $DNA$ or $RNA$,tagged with a radioactive molecule (probe),is allowed to hybridize to its complementary $DNA$ in a clone of cells,followed by detection using autoradiography.
The clone having the mutated gene will not appear on the photographic film because the probe will not have complementarity with the mutated gene.

Explore More

Similar Questions

What is used for the large-scale production of products in biotechnology?

Plasmid $pBR322$ has a $PstI$ restriction enzyme site within the gene $amp^R$ that confers ampicillin resistance. If this enzyme is used for inserting a gene for $\beta$-galactosidase production and the recombinant plasmid is inserted into an $E. coli$ strain:

Which of the following is $NOT$ a step in $r-DNA$ technology?

In a mixture,$DNA$ fragments are separated by

Given below are two statements.
Statement $I$ - The isolated $DNA$ of donor organism is cleaved by suitable restriction endonuclease to form $DNA$ fragments with cohesive staggered or blunt ends.
Statement $II$ - The foreign $DNA$ or passenger $DNA$ can also be obtained directly from genomic or cDNA library.
In the light of above statements,select the correct option given below:

Vedclass Products

For Students

Vedclass Test Series

Mock tests in real JEE/NEET style with performance analysis. 5-day free trial.

Start Free Trial
For Teachers

Exam Paper Generator

Generate Set A/B/C/D exam papers from 7.5L+ questions in 2 minutes. 3 chapters free.

Try Free
For Institutes

Online Exam Module

Live online exams with unlimited students, 360° analytics & white-label branding.

See Demo