Recall the experiments done by Frederick Griffith,Avery,MacLeod,and McCarty,where $DNA$ was speculated to be the genetic material. If $RNA$,instead of $DNA$,was the genetic material,would the heat-killed strain of $Pneumococcus$ have transformed the $R$-strain into a virulent strain? Explain.

(N/A) $RNA$ is chemically more labile and prone to degradation compared to $DNA$ due to the presence of the $2'-OH$ group in its ribose sugar.
Furthermore,$RNA$ is highly susceptible to enzymatic degradation by ribonucleases,which are ubiquitous in the environment.
Therefore,if $RNA$ were the genetic material,the heat-killed $S$-strain would likely have been degraded during the experimental process and would not have retained its ability to transform the $R$-strain into a virulent form.