Ribose and 2-deoxyribose can be differentiate | vedclass

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(D) Ribose is an aldopentose that reacts with phenylhydrazine $(Ph-NH-NH_2)$ to form a characteristic osazone derivative. In $2$-deoxyribose, the $-OH

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Osazone formation

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(D) Ribose is an aldopentose that reacts with phenylhydrazine $(Ph-NH-NH_2)$ to form a characteristic osazone derivative. In $2$-deoxyribose, the $-OH$ group at the $C-2$ position is replaced by a hydrogen atom. The formation of an osazone requires the presence of an $\alpha$-hydroxy carbonyl group (or a group that can be oxidized to it). Since $2$-deoxyribose lacks the $-OH$ group at the $C-2$ position, it cannot form the stable osazone structure under standard conditions, allowing it to be differentiated from ribose.

Ribose and $2$-deoxyribose can be differentiated by

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