Which combination is best for the preparation | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(C) The target compound $(A)$ is a chiral alkyne. To synthesize it,we need to perform an $S_N2$ reaction between a chiral alkyl halide and a nucleophi

Vedclass · Accepted Answer

Vedclass · Answer

(C) The target compound $(A)$ is a chiral alkyne. To synthesize it,we need to perform an $S_N2$ reaction between a chiral alkyl halide and a nucleophile. The reaction involves the nucleophilic attack of the acetylide ion on the primary carbon of the alkyl bromide. The stereocenter remains unaffected because the reaction occurs at the terminal primary carbon. The correct approach is to use the chiral alkyl bromide $(S)-2	ext{-bromobutane}$ derivative to maintain the configuration at the chiral center. Option $(C)$ correctly represents the sequence where the chiral center is preserved and the alkyne chain is extended.

Which combination is best for the preparation of the compound $(A)$ shown below?

Similar Questions

What is the increasing order of acidity for the following substances?
$(1)$ $CH_2=CH_2$
$(2)$ $CH_3-CH_3$
$(3)$ $HC \equiv CH$
$(4)$ $NH_3$

Describe the physical properties of alkynes.

What type of bonds are formed between two carbon atoms in acetylene?

The reagent$(s)$ for the following conversion is/are:
$Br-CH_2-CH_2-Br \xrightarrow{?} HC \equiv CH$

$R-CH_2-CCl_2-R \xrightarrow{\text{Reagent}} R-C \equiv C-R$
The reagent is

Vedclass Test Series

Exam Paper Generator

Online Exam Module