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(B) The first clinical gene therapy was performed in $1990$ on a $4$-year-old girl with adenosine deaminase $(ADA)$ deficiency.$ADA$ deficiency is cau

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Adenosine deaminase deficiency

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(B) The first clinical gene therapy was performed in $1990$ on a $4$-year-old girl with adenosine deaminase $(ADA)$ deficiency.$ADA$ deficiency is caused by the deletion of the gene for adenosine deaminase,which is crucial for the proper functioning of the immune system.In this therapy,lymphocytes from the patient's blood were grown in a culture outside the body,and a functional $ADA$ $cDNA$ was introduced into these lymphocytes using a retroviral vector.These genetically engineered lymphocytes were then returned to the patient's body.

The first clinical gene therapy was given for the treatment of .........

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