Select the best reagent to carry out the abov | vedclass

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(B) The starting material contains both a ketone group and an ester group (lactone). We need to selectively reduce the ketone to a secondary alcohol w

Vedclass · Accepted Answer

$NaBH_4$

Vedclass · Answer

(B) The starting material contains both a ketone group and an ester group (lactone). We need to selectively reduce the ketone to a secondary alcohol without affecting the ester group. $LiAlH_4$ is a strong reducing agent that would reduce both the ketone and the ester. $NaBH_4$ is a milder reducing agent that selectively reduces ketones and aldehydes to alcohols,but generally does not reduce esters under standard conditions. Therefore,$NaBH_4$ is the best reagent for this selective reduction.

Select the best reagent to carry out the above conversion.

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